Note that urine protein electrophoresis with immunofixation can be performed on spot or 24-hour urine collection. AL, light chain amyloidosis; ATTR, transthyretin amyloidosis; ATTRm, mutant transthyretin amyloidosis; ATTRwt, wild-type transthyretin amyloidosis; ECG, electrocardiography; Echo, echocardiogram; MGUS, monoclonal gammopathy of undetermined significance; MRI, magnetic resonance imaging. Figure modified with permission from Nativi-Nicolau and Maurer. Curr Opin Cardiol. 2018;33:571–579.