A8.

Lugano gastrointestinal lymphoma stage system

Stage	Definition
Stage IE	Lesions are limited to the gastrointestinal tract
IE1	Infiltrate to mucosa, submucosa
IE2	Infiltrate to muscularis propria, serosal layer
Stage II	Lesions spread to abdominal cavity
II1	Involvement of local lymph nodes
II2	Involvement of distant lymph nodes
Stage IIE	Penetration of serosa layer to adjacent organs or tissues
Stage IV	Disseminated involvement of extranodal organs or invasion of lymph nodes on upper side of diaphragm