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. 2019 Aug;31(4):578–585. doi: 10.21147/j.issn.1000-9604.2019.04.02

A2.

N stage

N stage No. of tumor-involved regional lymph nodes Presence of in-transit, satellite, and/or microsatellite metastases
NX Regional nodes not assessed (e.g., SLN biopsy not performed, regional nodes previously removed for another reason); Exception: pathological N category is not required for T1 melanomas, use clinical N information No
N0 No regional metastases detected No
N1 One tumor-involved node or any number of in-transit, satellite, and/or microsatellite metastases with no tumor-involved nodes
 N1a One clinically occult (i.e., detected by SLN biopsy) No
 N1b One clinically detected No
 N1c No regional lymph node disease Yes
N2 Two or 3 tumor-involved nodes or any number of in-transit, satellite, and/or microsatellite metastases with one tumor-involved node
 N2a Two or 3 clinically occult (i.e., detected by SLN biopsy) No
 N2b Two or 3, at least one of which was clinically detected No
 N2c One clinically occult or clinically detected Yes
N3 Four or more tumor-involved nodes or any number of in-transit, satellite, and/or microsatellite metastases with 2 or more tumor-involved nodes, or any number of matted nodes without or with in-transit, satellite, and/or microsatellite metastases
 N3a Four or more clinically occult (i.e., detected by SLN biopsy) No
 N3b Four or more, at least one of which was clinically detected, or the presence of any number of matted nodes No
 N3c Two or more clinically occult or clinically detected and/or presence of any number of matted nodes Yes