2.
Distribution and attributable proportion of HR-HPV genotypes among different grades of cervical lesions
| HR-HPV genotype | Normal pathology (n=9,252) | CIN1 (n=103) | CIN2+ (n=91) | Total population (n=9,526)*** | ||||||||
| n (%)* | Single infection (n) | Attributable proportion(%)** | n (%)* | Single infection (n) | Attributable proportion (%)** | n (%)* | Single infection (n) | Attributable proportion (%)** | n (%)* | Single infection (n) | Attributable proportion (%)** | |
| HR-HPV, high-risk human papillomavirus; CIN1, cervical intraepithelial neoplasia grade 1; CIN2+, cervical intraepithelial neoplasia grade 2 or worse; *, The total percentage of each HPV type is not necessarily equal to 100% because a result may be counted more than once in cases where the sampled lesion contained multiple HPV types; **, Proportion of multiple attributable fraction and number of single infection within HR-HPV positive women; ***, Eighty women who had no pathological results but had HPV tests results were also included in the total population analysis. A total of 238 women were positive in initial HPV results (careHPV or PCR HPV test without genotyping) but failed to be genotyped with specific genotypes, 232 of whom were pathologically normal, 5 of whom had CIN1, and 1 of whom had CIN2+. | ||||||||||||
| Any type | 1,611 | 951 | 100.00 | 98 | 50 | 100.00 | 90 | 49 | 100.00 | 1,874 | 1,089 | 100.00 |
| 16 | 187 (11.61) | 84 | 8.09 | 36 (36.73) | 13 | 30.68 | 68 (75.56) | 37 | 73.53 | 303 (16.17) | 140 | 12.09 |
| 18 | 83 (5.15) | 26 | 2.27 | 12 (12.24) | 3 | 5.64 | 6 (6.67) | 0 | 0.37 | 105 (5.60) | 31 | 2.41 |
| 31 | 113 (7.01) | 45 | 4.02 | 8 (8.16) | 2 | 3.40 | 8 (8.89) | 1 | 1.68 | 137 (7.31) | 49 | 3.91 |
| 33 | 141 (8.75) | 53 | 5.22 | 8 (8.16) | 1 | 2.01 | 9 (10.00) | 1 | 3.42 | 164 (8.75) | 56 | 4.71 |
| 35 | 66 (4.10) | 16 | 1.45 | 3 (3.06) | 1 | 1.13 | 3 (3.33) | 1 | 1.17 | 75 (4.00) | 19 | 1.45 |
| 39 | 152 (9.44) | 27 | 3.51 | 6 (6.12) | 0 | 0.00 | 1 (1.11) | 0 | 0.37 | 165 (8.80) | 28 | 3.09 |
| 45 | 45 (2.79) | 13 | 0.99 | 3 (3.06) | 2 | 2.11 | 1 (1.11) | 0 | 0.00 | 54 (2.88) | 16 | 1.06 |
| 51 | 204 (12.66) | 76 | 7.86 | 14 (14.29) | 2 | 5.45 | 6 (6.67) | 2 | 3.12 | 229 (12.22) | 81 | 7.20 |
| 52 | 359 (22.28) | 155 | 17.47 | 14 (14.29) | 3 | 7.29 | 16 (17.78) | 2 | 5.43 | 406 (21.66) | 164 | 16.32 |
| 53 | 297 (18.44) | 120 | 13.08 | 14 (14.29) | 4 | 8.14 | 14 (15.56) | 0 | 0.56 | 341 (18.20) | 126 | 12.39 |
| 56 | 176 (10.92) | 61 | 6.31 | 15 (15.31) | 7 | 10.60 | 6 (6.67) | 0 | 0.00 | 211 (11.26) | 73 | 6.49 |
| 58 | 290 (18.00) | 124 | 13.14 | 20 (20.41) | 4 | 8.62 | 15 (16.67) | 4 | 8.02 | 341 (18.20) | 140 | 13.04 |
| 59 | 103 (6.39) | 49 | 4.15 | 9 (9.18) | 5 | 6.81 | 2 (2.22) | 0 | 0.56 | 119 (6.35) | 55 | 4.08 |
| 66 | 146 (9.06) | 57 | 5.33 | 7 (7.14) | 1 | 1.73 | 2 (2.22) | 0 | 0.37 | 158 (8.43) | 60 | 4.83 |
| 68 | 243 (15.08) | 45 | 7.13 | 14 (14.29) | 2 | 6.39 | 6 (6.67) | 1 | 1.40 | 277 (14.78) | 51 | 6.92 |