Table 4:

Association of fibrosis severity with cognitive measures (N=378)

		Model 1		Model 2		Model 3
		β±SE	p-value	β±SE	p-value	β±SE	p-value
LMd	Int vs. Low	0.24±0.40	0.553	0.13±0.46	0.772	0.06±0.47	0.899
	High vs. low	0.28±0.69	0.680	−0.14±0.88	0.871	−0.37±0.90	0.679
VRd	Int vs. Low	0.47±0.31	0.130	0.25±0.35	0.474	0.28±0.36	0.429
	High vs. low	−0.04±0.53	0.934	−0.65±0.66	0.326	−0.54±0.67	0.424
TrB-TrA†	Int vs. Low	−0.004±0.024	0.868	−0.02±0.03	0.372	−0.02±0.03	0.375
	High vs. low	−0.05±0.04	0.239	−0.11±0.05	0.034	−0.11±0.05	0.028
SIM	Int vs. Low	0.25±0.38	0.51	0.04±0.44	0.923	0.009±0.440	0.984
	High vs. low	−1.67±0.65	0.011	−2.05±0.83	0.013	−2.22±0.83	0.009
HVOT†	Int vs. Low	0.06±0.06	0.367	0.03±0.07	0.666	0.02±0.07	0.736
	High vs. low	0.03±0.11	0.780	−0.003±0.14	0.981	−0.01±0.14	0.971

Values in bold indicate results with p-value≤0.05

^†Variable are log-transformed

Model 1: adjusted for age, sex, education, time between abdominal CT and cognitive tests, cohort

Model 2: adjusted for model 1 covariates plus BMI, alcohol, SBP, smoking, history of CVD, physical activity, CRP, the ratio of total cholesterol to HDL cholesterol, visceral adipose tissue, HOMA-IR

Model 3: adjusted for model 2 covariates plus diabetes status

LMd=Logical Memory Delayed Recall; VRd= Visual Reproduction Delayed Recall; TrB-TrA=Trail making B minus Trail making A; SIM=Similarities test; HVOT= Hooper Visual Organization test; CT=computed tomography; BMI=Body Mass Index; SBP=Systolic Blood Pressure; CVD=Cardiovascular Disease, CRP=C-Reactive Protein; HDL=high-density lipoprotein

Protein; HDL=high-density lipoprotein