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. Author manuscript; available in PMC: 2020 Sep 15.
Published in final edited form as: J Immunol. 2019 Aug 7;203(6):1650–1664. doi: 10.4049/jimmunol.1801236

Figure 3. Phenotype of IgM+, IgG+ and IgA+ DN B cells in the peripheral blood of HC and MS patients.

Figure 3.

(A) Representative surface staining of MS DN B cells for the indicated markers. IgM+ DN B cells (dashed line), IgG+ DN B cells (solid line) and IgA+ DN B cells (dotted line) are depicted. (B) Percentages of CD5+, CD10+, CD38+ and CD95+ cells within IgM+, IgG+ and IgA+ DN B cells in the peripheral blood of HC (n = 48) and MS patients (n = 96). Mean (bars) ± SD is depicted. The significance levels shown without bars indicate differences in 1 B cell subset between HC and MS patients. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001