Figure 9. CDR3 physicochemical properties of DN and IgD−CD27+ memory B cells of HC and MS patients.
H-CDR3 mean physicochemical properties for each subject are shown as a single point for both the DN and IgD−CD27+ memory B cell populations of HC and MS patients. Horizontal bars indicate the mean of the mean property scores with the vertical shading indicating ± 1 SD about the mean of means. (A-B) CDR3 hydrophobicity, basic aa, acidic aa, aromatic aa, charge, polarity and aa length are depicted. (C) CDR3 aa length is shown for the different IGHJ families. * FDR < 0.20 and p < 0.05