Table 1.
Characteristics of the Study Population by Diabetes Status, Reykjavik Study, 1968–2015
| Reykjavik Studya | AGES Studyb | ||||||
|---|---|---|---|---|---|---|---|
| Characteristic | Category | No T2D | T2D | % T2D | All women | Number | % T2D |
| Participants | Number | 9,312 | 294 | 3.1 | 9,606 | 3,103 | 10.1 |
| Breast cancer cases | Number | 712 | 16 | 2.2 | 728 | 93 | 11.88 |
| Deaths | Number | 6,544 | 255 | 3.8 | 6,799 | 1,414 | 12.6 |
| Person-years | Number | 266,738 | 6,023 | 2.2 | 272,761 | 30,769 | 9.5 |
| Follow-up time | Mean ± std | 28.6±11.5 | 20.5±10.9 | - | 28.4±11.6 | 9.9±3.4 | - |
| Age at cohort entry | Mean ± std | 53.0±8.9 | 60.4±9.2 | - | 53.2±9.0 | 76.8±5.9 | - |
| Age at breast cancer | Mean ± std | 69.7±11.2 | 73.1±9.7 | - | 69.7±11.2 | 82.0±6.3 | - |
| Age at diabetes | Mean ± std | NA | 56.8±11.7 | - | 56.8±11.7 | 75.5±9.4 | - |
| Height (cm) | Mean ± std | 163.2±5.7 | 161.8±6.0 | 163.1±5.7 | 160.6±5.8 | - | |
| Birth cohort | 1907–1914 | 1,348 | 97 | 6.7 | 1,445 | 72 | 12.3 |
| 1915–1919 | 1,636 | 53 | 3.1 | 1,689 | 298 | 10.5 | |
| 1920–1924 | 2,055 | 56 | 2.6 | 2,111 | 642 | 12.2 | |
| 1925–1929 | 2,058 | 48 | 2.3 | 2,106 | 850 | 10.7 | |
| 1930–1936 | 2,215 | 40 | 1.8 | 2,254 | 928 | 7.7 | |
| Location of early life residence | Reykjavik | 3,282 | 115 | 3.4 | 3,397 | 1,142 | 12.1 |
| Coastal area | 3,084 | 95 | 3.0 | 3,179 | 1,009 | 9.6 | |
| Rural | 2,445 | 69 | 2.7 | 2,514 | 796 | 8.0 | |
| Missing | 501 | 15 | 2.9 | 516 | 156 | 9.0 | |
| Education, yrs | Primary | 5,034 | 190 | 3.6 | 5,224 | 1,367 | 11.1 |
| Secondary | 3,495 | 88 | 2.4 | 3,583 | 1,396 | 9.2 | |
| College | 783 | 16 | 2.0 | 799 | 340 | 10.0 | |
| BMI, kg/m2 | <18.5 | 223 | 5 | 2.2 | 228 | 56 | 5.4 |
| ≥18.5 to <25 | 4,992 | 69 | 1.4 | 5,061 | 1,012 | 5.6 | |
| ≥25 to <30 | 3,083 | 113 | 3.5 | 3,196 | 1,258 | 9.6 | |
| ≥30 | 1,014 | 107 | 9.6 | 1,121 | 777 | 17.0 | |
| Smoking status | Never | 4,099 | 134 | 3.2 | 4,223 | 1,624 | 10.8 |
| Past | 1,418 | 70 | 4.7 | 1,488 | 993 | 10.0 | |
| Current | 3,795 | 90 | 2.3 | 3,885 | 377 | 8.8 | |
| Regular sports | No | 7,249 | 239 | 3.2 | 7,488 | 1,882 | 10.6 |
| Yes | 2,063 | 55 | 2.6 | 2,118 | 775 | 7.5 | |
| Age at menarche, yrs | ≤12 | 1,578 | 61 | 3.7 | 1,639 | 572 | 11.5 |
| 13 | 2,417 | 82 | 3.3 | 2,499 | 753 | 8.9 | |
| 14 | 2,710 | 49 | 1.8 | 2,759 | 972 | 9.4 | |
| ≥15 | 1,848 | 51 | 2.7 | 1,899 | 640 | 8.6 | |
| Missing | 759 | 51 | 6.3 | 810 | 166 | 20.5 | |
| Number of children | 0 | 937 | 40 | 4.2 | 977 | 218 | 8.3 |
| 1–2 | 2,452 | 53 | 2.1 | 2,505 | 661 | 3.3 | |
| ≥3 | 5,874 | 201 | 3.3 | 6,075 | 2,060 | 11.6 | |
| Missing | 49 | 0 | 0 | 49 | 164 | 20.7 | |
| Age at first live birth, | <25 | 4,654 | 137 | 2.9 | 4,792 | 1,788 | 8.3 |
| yrs | ≥25 | 3,059 | 77 | 2.3 | 3,136 | 893 | 9.5 |
| Missing | 662 | 40 | 6.5 | 702 | 204 | 9.5 | |
T2D diagnosis based on self-report (N=140) or elevated glucose levels (N=154).
Values are for exams conducted among AGES participants in 2002–20006.