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Structural comparison of apo- and citrate-bound MCP2201LBD. (A) The ligand-free (orange) and citrate-bound (green) structures were superimposed. The binding of citrate induced a series of conformation changes, including the movement of helix α1 (B), the unbending of helix α2 (C), and the swing of the C-terminus of helix α4 (D).
