Skip to main content
. Author manuscript; available in PMC: 2020 Sep 9.
Published in final edited form as: Curr Biol. 2019 Aug 15;29(17):2840–2851.e4. doi: 10.1016/j.cub.2019.07.027

Figure 4. Autophagy blocks developmental transition by disrupting ecdysone synthesis.

Figure 4.

(A) Quantification of ecdysone/20-hydroxyecdysone titers in fed and starved phm>yw, phm>Atg1RNAi and phm>RhebAV4 larvae at different timing stages. (B) Quantification of ecdysone/20-hydroxyecdysone levels in phmGS>yw, phmGS>Atg1 and phmGS>TSC½ larvae at different stages with or without 1.5 μg/ml RU486 feeding. (A and B) Mean ± SEM; p values by unpaired t-test (n=4; ns, not significant, ****p<0.0001).

See also Figure S4.