Fig. 7.

Effects of Prx5 deficiency on hepatic steatosis. (A) ROS level assessed by OxiSelect In Vitro ROS/RNS Kit in liver tissues. (B, C) Activities of serum alanine aminotranferase (ALT) and aspartate aminotranferase (AST) were measured by commercial kits. (D) Histological sections of the liver were stained with hematoxylin and eosin. (E) Lipid accumulation in mouse livers was assessed using Oil Red O staining. (F) Immunohistochemistry staining of SREBP-1, involved in lipogenesis in the liver tissues of WT and Prx5 −/− mice. WT mice were used as controls. Values are presented as mean ± standard deviation (n = 3). *, p < 0.05; ***, p < 0.001 vs. control. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)