Table 2. Diagnostic performance of predictors for identifying lymphoma-associated malignant pleural effusion.
Parameters | L-MPE (n=17) | TPE (n=216) | Sensitivity, % | Specificity, % | PPV, % | NPV, % | AUC |
---|---|---|---|---|---|---|---|
Fever | 2 | 104 | 12 [2–38] | 52 [45–59] | 2 [0–7] | 88 [81–93] | 0.68 [0.57–0.79] |
S-LDH >460 IU/L | 13 | 41 | 76 [50–92] | 81 [75–86] | 24 [14–38] | 98 [94–99] | 0.79 [0.67–0.91] |
No fever and S-LDH >460 U/L | 11 | 24 | 65 [39–85] | 89 [84–93] | 31 [17–49] | 97 [93–99] | 0.77 [0.63–0.91] |
Fever and S-LDH ≤460 U/L | 0 | 87 | 0 [0–23] | 60 [53–66] | 0 [0–5] | 88 [82–93] | 0.70 [0.61–0.80] |
Data are shown as number or % [95% CI]. L-MPE, lymphoma-associated malignant pleural effusion; TPE, tuberculous pleural effusion; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve; S-LDH, serum lactate dehydrogenase.