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. 2019 Aug;7(16):387. doi: 10.21037/atm.2019.07.43

Figure 3.

Figure 3

Comparison between the increase, no change, and decrease groups for (A) CD8, (B,C) PD-L1, (D) CD20, and (E) Foxp3 with respect to the interval of time between the 1st and 2nd surgery. The distributions of the three groups for (A) CD8, (B) PD-L1(T), (C) PD-L1(L), (D) CD20, and (E) Foxp3 are displayed, and their relationships with the interval of time were analyzed. A fold change in the relative value (2nd surgery/1st surgery) of >2 (increase group) or <0.5 (decrease group) for (A) CD8, (B) PD-L1(T), (C) PD-L1(L), (D) CD20, and (E) Foxp3 was defined as significant, and patients were divided into three groups (increase, no change, and decrease). PD-L1, programmed cell death ligand 1; PD-L1(T), PD-L1 in tumor cells; PD-L1(L), PD-L1 in lymphocytes.