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. 2019 Sep 10;10(9):655. doi: 10.1038/s41419-019-1911-8

Fig. 3. MPS-1-regulated cell proliferation and apoptosis of CRC cells.

Fig. 3

a, b The efficiency of MPS-1 gene knockdown in RKO cells was evaluated by qPCR a and WB b. c–f MPS-1 gene knockdown suppressed cell proliferation c and colony formation d, and induced apoptosis e and activity of Caspase 3/7 f in RKO cells. g, h The efficiency of MPS-1 gene over-expression in Caco2 cells was evaluated by qPCR g and WB h. i–l Over-expression of MPS-1 in RKO cells promoted cell proliferation i and colony formation j, and suppressed apoptosis k and activity of Caspase 3/7 l. Error bars indicate SD of three biological replicates. *P < 0.05, **P < 0.01, ***P < 0.001