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. 2019 Sep 10;9:13020. doi: 10.1038/s41598-019-49448-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cartoon depiction of the different transmit sequences used in this study. Focused scans acquire a single lateral location of an image at a time and are focused at a single depth. Plane wave scans sacrifice transmit focusing and involve transmitting from all elements at once to insonify the entire field of view. Plane wave synthetic focusing (PWSF) involves transmitting multiple angled plane waves and then summing them to gain transmit focusing throughout the image (i.e., at all depths and lateral locations).