Table 1.
Donor | Tissue | Location | Aetiology | Age | Previous treatment | Skin colour | Pt age | Gender |
---|---|---|---|---|---|---|---|---|
1 2 |
Nskin N mono |
Abdomen NA |
NA NA |
NA NA |
NA NA |
Unknown White |
44 yrs 53 yrs |
Female Female |
3 4 |
Nskin N mono |
Abdomen NA |
NA NA |
NA NA |
NA NA |
Unknown White |
41 yrs 50 yrs |
Female Female |
5 6 |
Nskin N mono |
Unknown NA |
NA NA |
NA NA |
NA NA |
White Unknown |
42 yrs 50 yrs |
Female Female |
7 8 |
Kscar Ks mono |
Abdomen NA |
Surgery NA |
2 yrs NA |
None NA |
Dark brown Dark brown |
40 yrs 55 yrs |
Female Female |
9 10 |
Kscar Ks mono |
Earlobe NA |
Piercing NA |
4 yrs NA |
None NA |
Dark brown Dark brown |
20 yrs 20 yrs |
Male Female |
11a 12a |
Kscar Ks mono |
Sternum NA |
Surgery NA |
10 yrs NA |
Corticosteroids NA |
Dark brown Dark brown |
26 yrs 26 yrs |
Female Female |
Overview of the characteristics of the tissue samples used for the construction of the SE. All the skin models were constructed using donor-matched keratinocytes and fibroblasts; note that each tissue donor is followed by the co-cultured monocyte donor below so that each table row represents the combination of donors used per co-culture
NA not applicable, Donor age in years (yrs), Nskin normal skin, Kscar keloid scar, N mono normal monocytes, Ks mono keloid monocytes
aThe only SE and mono from the same donor