Table 6.

Regression coefficients of CCD results of optimization of uricase production by Aspergillus welwitschiae.

Factor	Coefficient estimate	Standard error	95% CI Low	95% CI High
Intercept	58.08	0.92	56.04	60.12
X1 - (incubation time)	2.98	0.61	1.62	4.33
X2 - (inoculum size)	0.98	0.61	−0.37	2.34
X3 - (yeast extract)	−2.38	0.61	−3.73	−1.02
X1 X2	0.06	0.79	−1.71	1.83
X1 X3	−1.57	0.79	−3.34	0.21
X2 X3	−1.80	0.79	−3.57	−0.03
X12	−2.36	0.59	−3.68	−1.04
X22	−6.87	0.59	−8.19	−5.55
X32	−7.52	0.59	−8.84	−6.20