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. 2019 Sep 4;10:1947. doi: 10.3389/fmicb.2019.01947

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Copyright © 2019 Kim, Lee, An, Song, Lee, Kim and Kong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Significant differences in bacterial abundance according to diet and statin therapy. (A) Comparison between RD, HFD, and HFD-Ator groups. (B) Comparison between RD, HFD, and HFD-Rosu groups. (C) Comparison between HFD-Ator and HFD-Rosu groups. Significant differences were identified by LEfSe analysis at P < 0.05 by the Kruskal–Wallis test (among classes) and Wilcoxon test (between subclasses). The threshold logarithmic LDA score was 3.0. Three and four bacterial families were identified by atorvastatin and rosuvastatin, respectively. Among them, Odoribacteraceae, Deferribacteraceae, and Bacteroidaceae overlapped. At the genus level, Bacteroides, Butyricimonas, and Mucispirillum were increased by both atorvastatin and rosuvastatin.