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GYY4137 elevates MIP-2 concentration in inflamed paws of TRPA1 KO mice. Concentrations of IL-1β, KC, MIP-1α and MIP-2 in lavage fluid of the subcutaneous tissue of the inflamed hind paws of GYY4137-treated (50 mg kg−1 day −1 i.p.) and vehicle-treated TRPA1 WT and KO mice undergoing K/BxN arthritis measured at day 3. Data are mean ± SEM of n = 6–8 mice per group, *p < 0.05 vs. GYY4137-treated TRPA1 WT animals.
