TABLE 3.
Differentially expressed genes under bile exposure in L. monocytogenesΔsigBCHL quadruple mutant.
| LMRG Locus tag | lmo Locus tag | Gene name | Operon | Annotation | FC | Adjusted p-value |
| LMRG_00151 | LMRG_02887, LMRG_00151-LMRG_00152 | Hypothetical protein | 2.23 | 0.00 | ||
| LMRG_01622 | lmo2210 | Hypothetical protein | 4.25 | 0.00 | ||
| LMRG_01645 | lmo2187 | Hypothetical protein | 2.22 | 0.02 | ||
| LMRG_01919 | lmo2778 | Hypothetical protein | 2.05 | 0.03 | ||
| LMRG_02808 | lmo2132 | Cyclic nucleotide-binding protein | 2.08 | 0.00 | ||
| LMRG_00091 | lmo0398 | LMRG_00091-LMRG_00095 | PTS system, IIA component | −2.51 | 0.01 | |
| LMRG_00092 | lmo0399 | PTS system, IIB component | −3.52 | 0.00 | ||
| LMRG_00352 | lmo0665 | LMRG_00351-LMRG_00353 | Hypothetical protein | −2.32 | 0.01 | |
| LMRG_00353 | lmo0666 | Domain-containing protein | −2.12 | 0.01 | ||
| LMRG_00369 | lmo0681 | Flagellar biosynthesis regulator FlhF | −2.01 | 0.00 | ||
| LMRG_00373 | lmo0685 | motA | motAB | Flagellar motor rotation protein MotA | −2.43 | 0.00 |
| LMRG_00852 | lmo1400 | LMRG_00852-LMRG_00854 | phosphinothricin N-acetyltransferase | −2.06 | 0.00 | |
| LMRG_01073 | lmo1926 | LMRG_01075-LMRG_01070 | Chorismate mutase II | −2.2 | 0.01 | |
| LMRG_01156 | lmo2008 | LMRG_01157-LMRG_01155 | ABC transporter, permease protein | −2.71 | 0.02 | |
| LMRG_01228 | lmo2077 | LMRG_01229-LMRG_01228 | Inactive homolog of metal-dependent proteases, Putative molecular chaperone tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB | −2.61 | 0.00 | |
| LMRG_01283 | lmo2129 | Hypothetical protein | −2.03 | 0.00 | ||
| LMRG_01286 | lmo1681 | metE | LMRG_01286-LMRG_01288 | 5-methyltetrahydropteroyl-triglutamate–homocysteine methyltransferase | −2.23 | 0.00 |
| LMRG_01287 | lmo1680 | Cystathionine gamma-synthase | −2.59 | 0.04 | ||
| LMRG_01333 | lmo1633 | trpE | trp | Anthranilate synthase, aminase component | −2.21 | 0.00 |
| LMRG_01428 | lmo1542 | rplU | LMRG_01428-LMRG_01430 | 50S ribosomal protein L21 | −3.22 | 0.00 |
| LMRG_01435 | lmo1535 | LMRG_01435-LMRG_01436 | YebC/PmpR family DNA-binding transcriptional regulator | −2.25 | 0.00 | |
| LMRG_01591 | lmo2241 | LMRG_01591-LMRG_01593 | Transcriptional regulator, GntR family | −2.25 | 0.00 | |
| LMRG_01669 | lmo2163 | LMRG_01669-LMRG_01673 | Myo-inositol 2-dehydrogenase 1, Oxidoreductase | −2.21 | 0.00 | |
| LMRG_01810 | lmo2438 | ClbS/DfsB family four-helix bundle protein | −2.97 | 0.00 | ||
| LMRG_01955 | lmo2741 | LMRG_01955-LMRG_01957 | Multidrug-efflux transporter, major facilitator superfamily (MFS);Efflux pump Lde | −2.62 | 0.00 | |
| LMRG_02234 | lmo2688 | LMRG_02235-LMRG_02233 | Cell division protein FtsW | −2.56 | 0.01 | |
| LMRG_02481 | lmo0052 | LMRG_02481-LMRG_02483 | Phosphoesterase, DHH family protein | −2.07 | 0.00 | |
| LMRG_02665 | lmo0241 | LMRG_02938, LMRG_02667-LMRG_02664 | TrmH family tRNA/rRNA methyltransferase YacO | −2.67 | 0.00 | |
| LMRG_02671 | lmo0235 | ispD1 | LMRG_02672-LMRG_02669 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase | −2.27 | 0.00 |