Table 1.
Selective adenosine receptor subtype agonists and antagonists implemented in this study. The Ki values come from the Nomenclature and Classification of Adenosine receptors—an update (Fredholm et al. 2011 [31])
| Adenosine receptor | Agonist | Antagonist |
|---|---|---|
| A1 | N6-cyclopentyladenosine (CPA) Ki value 2.3 nM | 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX)Ki value 3.0 nM |
| A2A | 2-p-(2-carboxyethyl) phenethylamino-5′-N-ethylcarboxamidoadenosine (CGS21680) Ki value 27 nM |
4-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol (ZM241385) Ki value 1.6 nM |
| A2B | 5′-N-ethylcarboxamido (NECA) Ki value 140 nM |
N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl) phenoxy]-acetamide (MRS1754) Ki value 1.97 nM |