Figure 6.

Ryr1 transcript levels are reduced in quadriceps muscle of Ryr1^WT/Indel and Ryr1^TM/Indel mice. (A) Representative agarose gel of Ryr1 (lower band) and Gapdh loading control (upper band) amplification products. (B, C) Quantitative analysis of Ryr1 (B) and DHPR (C) transcript levels in quadriceps muscles obtained by semiquantitative PCR using 6-FAM-labelled primers. Data are shown as mean ± SEM from five Ryr1^WT/WT, six Ryr1^WT/Indel, three RyR1^WT/TM and three Ryr1^TM/Indel mice (^*P < 0.05).