Table 6.
3-year disease-free survival |
ES group (n = 56) |
BTS group (n = 32) |
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Univariate | Multivariate | Univariate | Multivariate | |||||
Characteristic | HR (95%CI) | P-value | HR (95%CI) | P-value | HR (95%CI) | P-value | HR (95%CI) | P-value |
CEA (≥ 5 ng/mL vs <5 ng/mL) | 1.71 (0.74-3.95) | 0.209 | 2.67 (0.72-9.90) | 0.141 | ||||
ASA (Grade ≥ III vs Grade < III) | 0.890 (0.36-2.23) | 0.803 | 1.49 (0.41-5.43) | 0.542 | ||||
pT stage (pT3-4 vs pT1-2) | 2.26 (0.85-6.02) | 0.104 | 2.48 (0.55-11.18) | 0.239 | ||||
pN stage (pN+ vs pN0) | 1.48 (0.64-3.43) | 0.361 | 2.48 (0.55-11.18) | 0.239 | ||||
LVI (+) vs LVI (-) | 2.92 (1.25-6.81) | 0.013 | 1.97 (0.66-5.88) | 0.224 | ||||
NLR ≥ 19.3 vs NLR < 19.3 | 2.76 (1.02-7.45) | 0.046 | ||||||
dNLR ≥ 1.57 vs dNLR < 1.57 | 2.85 (1.17-6.95) | 0.021 | 3.02(1.23-7.42) | 0.016 | ||||
PLR ≥ 317 vs PLR < 317 | 1.55 (0.66-3.67) | 0.314 | ||||||
SII ≥ 3645 vs SII < 3645 | 2.04 (0.86-4.83) | 0.104 | ||||||
LMR ≥ 1.67 vs LMR < 1.67 | 2.54 (0.83-7.80) | 0.091 | 3.11 (1.13-8.54) | 0.052 | ||||
Chemotherapy (+) vs (-) | 0.95 (0.41-2.19) | 0.896 | 1.44 (0.47-4.41) | 0.523 |
SEMS: Self-expanding metal stents; BTS: Bridge to surgery; dNLR: Derived neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; SII: Systemic immune inflammation index; LMR: Lymphocyte-to-monocyte ratio; LVI: Lymphovascular invasion. Chemotherapy (+), accept chemotherapy lately. Chemotherapy (-), refuse to chemotherapy lately. P < 0.05 was considered significant.