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. 2019 Sep 7;25(33):4904–4920. doi: 10.3748/wjg.v25.i33.4904

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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Quantitative histopathological changes in ob/ob mice fed amylin liver non-alcoholic steatohepatitis (AMLN) or Gubra amylin non-alcoholic steatohepatitis (GAN) diet for 16 wk. Fractional (%) area of steatosis (hematoxylin-eosin staining), inflammation [galectin-3 immunostaining and fibrosis (collagen-1a1) immunostaining] determined by imaging-based morphometry (n = 8-10 mice per group). A: Steatosis; Galectin-3; C: Collagen-1a1. Scale bar 100 µm. AMLN: Amylin liver non-alcoholic steatohepatitis diet; GAN: Gubra amylin non-alcoholic steatohepatitis diet; Col1a1: Collagen-1a1.