Skip to main content
. 2019 Sep 10;3(17):2642–2652. doi: 10.1182/bloodadvances.2019000360

Figure 2.

Figure 2.

CLL cells reside in an immunosuppressive context in the LN. Lymphocyte analysis in PB and LN samples from untreated CLL patients (PB, n = 42; LN, n = 28) and HCs (PB, n = 10; LN, n = 5) by flow cytometry. Percentage of Tfh (CXCR5+PD-1+) cells (A) and Tregs (CD25+FoxP3+) (B) within CD4+ T cells. (C) Correlation between the percentage of Tregs of CD4+ T cells in the CLL LN and the absolute leukocyte count (ALC). (D) Percentage of PD-1+ cells within CD8+ T cells. ***P < .001, ****P < .0001, 1-way ANOVA followed by Sidak’s multiple-comparisons test (A-B,D), Pearson correlation analysis (C).