Fig. 4.

Histone deacetylase 4 (HDAC4) overexpression suppressed cardiac function recovery in the post-myocardial infarcted (MI) heart. Echocardiographic measurements of ventricular functional parameters at 2-mo-old mice in the post-MI heart. A: representative images are shown as the M-mode short-axis ultrasound among the groups. B and C: left ventricle internal diameter at end diastole (LVIDd) and end systole (LVIDs). D and E: left ventricle posterior wall thickness at end diastole (LVPWd) and end systole (LVPWs). F and G: ejection fraction (EF) and fraction shortening (FS). Values represent means ± SE (n = 5/group). *P < 0.05. Tg, transgenic.