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. 2019 Sep 11;2019(9):CD000371. doi: 10.1002/14651858.CD000371.pub7

Kloetzel 1982.

Methods RCT
Length of follow‐up: 10 months
Participants All children living in endemic area
Number analysed for primary outcome: 337; unclear how many randomized
Age range: 1 to 8 years old
Inclusion criteria: enlisted from 9 rural communities in Pariquera‐Acu state of Sao Paulo
Exclusion criteria: none stated
Interventions Single dose vs placebo
  • Mebendazole: 100 mg twice per day for 3 days

  • Placebo

Outcomes
  • Weight

  • Height

  • Head, chest, and mid‐arm circumference

  • Triceps skinfold

  • Stool egg counts (Kato‐Katz)

Notes Location: Cameroon
Burden: high
Results reported as changes in nutritional status grouped into 3 categories: improved, deteriorated, no change (unclear on basis of which parameter), and proportions compared
Source of funding: Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP).
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "Randomized", no further details provided.
Allocation concealment (selection bias) Unclear risk No details reported.
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Described as double‐blind, no details reported.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk No details about losses to follow‐up reported; quote: "the present report only deals with those 337 that could be followed throughout the entire 10 months". Inclusion of all randomized participants (number evaluable/number randomized): unclear (337 analysed).
Selective reporting (reporting bias) Low risk All stated outcomes reported.
Other bias Low risk No obvious other sources of bias.