TABLE 1.
Antibiotic susceptibility profiles of the carbapenem-resistant E. coli strains and the corresponding transconjugants to different antibiotics (mg/L).
| Isolates |
Antibioticsa
|
||||||||
| MEM | STR | ATM | AMX | CQM | FFC | DOX | ENR | CL | |
| L33 | 128 | 128 | 256 | >64 | >128 | >64 | 32 | 16 | 1 |
| L37 | 128 | 64 | 32 | >64 | >128 | >64 | 16 | 16 | 1 |
| L41-1 | 128 | 16 | 4 | >64 | >128 | >64 | 32 | ≤0.125 | 1 |
| L43-1 | 256 | 32 | 8 | >64 | >128 | >64 | 32 | 0.25 | 1 |
| L53 | 128 | 128 | 256 | >64 | >128 | >64 | 32 | 4 | 1 |
| L56 | 128 | >128 | >256 | >64 | >128 | >64 | 16 | 8 | 1 |
| L65 | 128 | 1 | ≤ 0.5 | >64 | >128 | >64 | 32 | 1 | 1 |
| L99 | 128 | >128 | >256 | >64 | >128 | >64 | 32 | 4 | 1 |
| L100 | 128 | 64 | 32 | >64 | >128 | >64 | 32 | ≤0.125 | 0.5 |
| L102 | 128 | 32 | 8 | >64 | 128 | 4 | 16 | ≤0.125 | 1 |
| L103-1 | 64 | 128 | >256 | >64 | >128 | >64 | 16 | 8 | 0.125 |
| L103-2 | 128 | 64 | 256 | >64 | >128 | >64 | 16 | ≤0.125 | 1 |
| L33T | 128 | 1 | ≤0.5 | >64 | 128 | 8 | 4 | ≤0.125 | 0.5 |
| L37T | 32 | 1 | ≤0.5 | >64 | 128 | 8 | 4 | ≤0.125 | 0.5 |
| L41-1T | 64 | 0.5 | 2 | >64 | >128 | 4 | 8 | ≤0.125 | 0.5 |
| L43-1T | 64 | 1 | 1 | >64 | >128 | 8 | 8 | ≤0.125 | 0.25 |
| L53T | 128 | 1 | 64 | >64 | 128 | 8 | 4 | ≤0.125 | 1 |
| L56T | 64 | 1 | ≤0.5 | >64 | 128 | 4 | 4 | ≤0.125 | 0.5 |
| L65T | 64 | 1 | ≤0.5 | >64 | 128 | 4 | 2 | ≤ 0.25 | 0.5 |
| L99T | 64 | 2 | ≤ 0.5 | >64 | 64 | 4 | 2 | ≤ 0.125 | 1 |
| L100T | 64 | 1 | 2 | >64 | 128 | 4 | 2 | ≤0.125 | 1 |
| L102T | 128 | 1 | 1 | >64 | >128 | 4 | 4 | ≤ 0.125 | 0.5 |
| L103-1T | 128 | 1 | ≤ 0.5 | >64 | 128 | 8 | 4 | ≤ 0.125 | 1 |
| L103-2T | 64 | 1 | 64 | >64 | 128 | 4 | 8 | ≤0.125 | 1 |
| J53b | ≤0.25 | 1 | ≤0.5 | 1 | ≤0.25 | 4 | 4 | ≤0.125 | 0.5 |
| ATCC25922c | ≤0.25 | 0.5 | ≤0.5 | 1 | ≤0.25 | 2 | 0.5 | ≤0.125 | 0.5 |
aMEM, meropenem; STR, streptomycin; ATM, aztreonam; AMX, amoxicillin; CQM, cefquinome; FFC, florfenicol; DOX, doxycycline; ENR, enrofloxacin; CL, colistin. All susceptibility tests were repeated at least three times according to CLSI method. The results of colistin susceptibility were interpreted according to EUCAST breakpoints. brecipient strain. cquality control strain.