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. Author manuscript; available in PMC: 2019 Sep 11.
Published in final edited form as: Prog Mol Biol Transl Sci. 2018 Aug 28;160:105–171. doi: 10.1016/bs.pmbts.2018.07.008

Figure 1:

Figure 1:

Schematic overview of (1) estrogen-mediated nongenomic signaling pathways via G protein-coupled estrogen receptors and membrane subpopulation of estrogen receptors, and (2) genomic signaling pathways via nuclear estrogen receptors in neural cells.

Akt: protein kinase B; ER: estrogen receptor; ERK: extracellular-regulated kinase; GPER: G protein-coupled estrogen receptor; MAPK: mitogen-activated protein kinase; PI3K: phosphoinositide-3 kinase; PKA: protein kinase A; PKC: protein kinase C; PLC: phospholipase C; RAS: RAS protein; Src: Src kinase; TF: transcription factor.