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. 2019 Sep 11;14:307. doi: 10.1186/s13018-019-1307-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — ICA protected rat against osteoarthritis. a H&E staining and safranin O/fast green staining were used to evaluate cartilage histopathology in OA rats, and immunohitochemical analysis was used to detect NLRP3 in OA rat cartilage tissue. b Statistical analysis of NLRP3 positive rate. All the results were shown as mean ± SD (n = 3), which were three separate experiments performed in triplicate. *p < 0.05 and **p < 0.01