Table 3.
At allograft IgAN diagnosis | After 6 months | |||||
---|---|---|---|---|---|---|
Dipstick albuminuria | None or trace | 1+ | ≥2+ | None or trace | 1+ | ≥2+ |
No medication (N = 216) | 143 (66.2%) | 22 (10.2%) | 51 (23.6%) | 166 (76.9%) | 26 (12.0%) | 24 (11.1%) |
Single RAASB (N = 38) | 9 (23.7%) | 8 (21.1%) | 21 (55.3%) | 18 (47.4%) | 7 (18.4%) | 13 (34.2%) |
Single BB/CCB (N = 28) | 19 (67.9%) | 5 (17.9%) | 4 (14.3%) | 15 (53.6%) | 4 (14.3%) | 9 (32.1%) |
Combination (N = 94) | 34 (36.2%) | 10 (10.6%) | 50 (53.2%) | 33 (35.1%) | 18 (19.1%) | 43 (45.7%) |
Blood pressure | Systolic BP | Diastolic BP | MAP | Systolic BP | Diastolic BP | MAP |
No medication (N = 268) | 129.0 [117.0–138.0] | 78.0 [70.0–85.5] | 95.0 [85.5–102.7] | 125.0 [116.0–135.0] | 76.0 [68.0–84.0] | 92.7 [84.5–100.2] |
Single RAASB (N = 33) | 120.0 [110.0–133.0] | 74.0 [65.0–80.0] | 88.7 [81.7–98.7] | 122.0 [118.0–136.0] | 81.0 [72.0–88.0] | 94.7 [90.0–103.3] |
Single BB/CCB (N = 28) | 120.0 [114.5–136.0] | 79.0 [69.5–87.0] | 93.2 [84.5–100.3] | 126.5 [116.5–140.0] | 79.0 [70.5–84.0] | 94.2 [85.8–103.3] |
Combination (N = 104) | 129.0 [118.5–139.5] | 80.0 [70.0–88.0] | 96.3 [88.0–103.3] | 128.0 [116.0–140.0] | 79.0 [70.0–87.0] | 93.7 [85.0–103.8] |
IgAN Immunoglobulin A nephropathy, RAASB Renin-angiotensin-aldosterone blockades, BB Beta blockers, CCB Calcium channel blockers, BP Blood pressure, MAP Mean arterial pressure