Table 3.
Multivariate analysis of prognostic variables including classical prognostic factors and CD68 for disease-free survival in breast cancer patients
| Variables | Hazard ratio | 95% CI | P | |
|---|---|---|---|---|
| Lower | Upper | |||
| TNM stage (II + I vs. III) | 1.806 | 1.086 | 3.004 | 0.023 |
| Histological grade (grade 1 + 2 vs. grade 3) | 3.487 | 2.158 | 5.636 | < 0.001 |
| Lymph node metastasis (no vs. yes) | 2.867 | 1.455 | 5.648 | 0.002 |
| ER status (negative vs. positive) | 0.627 | 0.351 | 1.120 | 0.115 |
| PR status (negative vs. positive) | 1.236 | 0.713 | 2.143 | 0.450 |
| HER2 gene (non-amplification vs. amplification) | 1.865 | 1.148 | 3.029 | 0.012 |
| CD68 (low expression vs. high expression) | 1.507 | 0.791 | 2.873 | 0.212 |
Significant P-values are shown in italic type