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. 2018 Dec 3;13(8):E236–E248. doi: 10.5489/cuaj.5598

Table 4.

Multivariate negative binomial regression comparing five-year total costs of treatment and treatment related complications in men who received surgery to men who received radiation therapy for treatment of localized prostate cancer

Group Year 1 Year 2 Year 3 Year 4 Year 5
Entire cohort

 Surgery 1.00 1.00 1.00 1.00 1.00
 Radiation therapy 0.82 (0.8–0.84) p<0.0001) 1.01 (0.95–1.07) p=0.76 1.17 (1.1–1.25) p<0.0001 1.29 (1.2–1.37) p<0.0001 1.30 (1.21–1.39) p<0.0001
Men aged 55–65 and ADG5
 Surgery 1.00 1.00 1.00 1.00 1.00
 Radiation therapy 0.88 (0.84–0.91) p<0.0001 0.96 (0.88–1.04) p=0.31 0.91 (0.83–1.00) p=0.04 1.5 (1.33–1.62) p<0.0001 1.4 (1.29–1.6) p<0.0001
Men aged >65 years
 Surgery 1.00 1.00 1.00 1.00 1.00
 Radiation therapy 0.81 (0.79–0.84) p<0.0001 1.11 (1.04–1.18) p<0.0001 1.44 (1.35–1.54) p<0.0001 1.28 (1.19–1.38) p<0.0001 1.28 (1.18–1.38) p<0.0001

Data are relative rates (RR), (95% confidence interval [CI]). Multivariate model also includes age, comorbidity (aggregated diagnosis groups [ADG] case mix), year of treatment, and income. ADG: aggregated diagnosis groups.