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Forkhead box P4 (FOXP4) was a direct target of miR-299-3p. (A) Putative binding site between miR-299-3p and the 3′-UTR of FOXP4. Relative luciferase activity in (B) SCC-4 and (C) SCC-9 cells transfected with miR-299-3p mimic or NC-miR and wt-FOXP4 and mt-FOXP4 (ns, not significant, ***P < .001). miR-299-3p indicates microRNA-299-3p; mt, mutant type; NC-miR, negative control miRNA; 3′-UTR, 3′-untranslated region; wt, wild type.
