Table 1b.
Patient and disease characteristics for both MSKCC and CCF patients (N=16,341) stratified by clinical D’Amico risk.
| Low Risk (N=6371) | Intermediate or High Risk (N=9970) | |
|---|---|---|
| Median at age surgery (IQR) | 59 (55, 64) | 62 (57, 66) |
| Median pre-operative PSA (IQR) (N=16153) | 5.0 (3.8, 6.4) | 6.2 (4.4, 10.5) |
| Biopsy Gleason score (N=15941) | ||
| ≤6 | 6371 (100%) | 1617 (17%) |
| 7 | 0 (0%) | 6329 (66%) |
| 8–10 | 0 (0%) | 1624 (17%) |
| Clinical T stage (N=16092) | ||
| T0 | 0 (0%) | 11 (0.1%) |
| T1 | 5098 (80%) | 4863 (50%) |
| T2 | 1273 (20%) | 4294 (44%) |
| T3 | 0 (0%) | 549 (5.6%) |
| T4 | 0 (0%) | 4 (<0.1%) |
| Clinical D’Amico risk classification | ||
| Low | 6371 (100%) | 0 (0%) |
| Intermediate | 0 (0%) | 7045 (71%) |
| High | 0 (0%) | 2925 (29%) |
| Pathologic Gleason Score (N=15159) | ||
| ≤6 | 3176 (52%) | 1147 (13%) |
| 7 | 2895 (47%) | 6593 (73%) |
| 8–10 | 60 (1.0%) | 1288 (14%) |
| ECE (N=16287) | 1016 (16%) | 4541 (46%) |
| Seminal vesicle invasion (N=16282) | 70 (1.1%) | 1336 (13%) |
| Lymph node invasion (N=16329) | ||
| Positive | 23 (0.4%) | 947 (10%) |
| Negative | 3712 (58%) | 8494 (85%) |
| No LND performed | 2632 (41%) | 521 (5.2%) |
| Positive surgical margins (N=16298) | 1027 (16%) | 2509 (25%) |
| Year of surgery | ||
| 1987–1990 | 68 (1.1%) | 258 (2.6%) |
| 1991–1995 | 389 (6.1%) | 887 (8.9%) |
| 1996–2000 | 1146 (18%) | 1330 (13%) |
| 2001–2005 | 2515 (39%) | 2317 (23%) |
| 2006–2010 | 1717 (27%) | 2889 (29%) |
| 2011–2015 | 536 (8.4%) | 2289 (23%) |