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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: BJU Int. 2018 Jun 22;122(6):1003–1009. doi: 10.1111/bju.14418

Table 2b.

Univariable and multivariable analysis of the association between preoperative risk and distant metastasis in patients with adverse pathology.

Adverse Feature
(Low-risk vs. Intermediate/High Risk)
Univariable Multivariable
HR (95% CI) p value HR (95% CI) p value
Extracapsular extension 0.14 (0.09, 0.22) <0.0001 0.32 (0.19, 0.51) <0.0001
Seminal vesicle invasion 0.24 (0.10, 0.57) 0.001 0.30 (0.12, 0.73) 0.008
Pathologic Gleason 7+ 0.12 (0.08, 0.18) <0.0001 0.30 (0.20, 0.47) <0.0001
Lymph node invasion 0.10 (0.01, 0.70) 0.020 0.09 (0.01, 0.69) 0.020