. Author manuscript; available in PMC: 2019 Dec 1.

Published in final edited form as: BJU Int. 2018 Jun 22;122(6):1003–1009. doi: 10.1111/bju.14418

Table 2c.

Univariable and multivariable analysis of the association between preoperative risk and death from prostate cancer in patients with adverse pathology.

Adverse Feature (Low-risk vs. Intermediate/High Risk)	Univariable		Multivariable
	HR (95% CI)	p value	HR (95% CI)	p value
Extracapsular extension	0.15 (0.07, 0.29)	<0.0001	0.40 (0.19, 0.84)	0.015
Seminal vesicle invasion	0.37 (0.14, 0.99)	0.047	0.47 (0.17, 1.28)	0.14
Pathologic Gleason 7+	0.19 (0.11, 0.33)	<0.0001	0.48 (0.26, 0.87)	0.016
Lymph node invasion	0.20 (0.03, 1.42)	0.11	0.19 (0.03, 1.35)	0.10