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Targeted deletion of Ccdc151 in mice leads to left-right asymmetry defect, a trait of the PCD disease. (A) Ccdc151-knockout animals presented with situs solitus (SS), situs inversus totalis (SIT) and situs inversus abdominalis (SIA). RV, right ventricle; LV, left ventricle; St, stomach; 1-5 (white numbers), numeration of lung lobes; 1-3 (black numbers), numeration of liver lobes. (B) Summary of the phenotypes observed in Ccdc151-knockout animals.
