Table 1.
Biomarker | Coefficient | p-value | Odds ratio | LOO Coeff SD | k-fold cross-validation coeff SD |
---|---|---|---|---|---|
Intercept | −3.5270 | 4.04e−11 | 0.0294 | 0.11 | 0.21 |
CA125 | 0.8217 | 6.45e−11 | 2.27 | 0.025 | 0.037 |
Protein Z | 0.5345 | 8.72e−4 | 1.71 | 0.028 | 0.055 |
LCAT | 0.3595 | 0.0211 | 1.43 | 0.024 | 0.059 |
CRP | 0.3419 | 0.0260 | 1.41 | 0.043 | 0.065 |
Table showing, for each biomarker; the model coefficients p-value indicating significance of contribution to the model by the Wald test; the odds ratio, indicating the contribution of each additional step up on the dysregulation score, for that biomarker, to the risk attribution of the sample; leave-one-out (LOO) coefficient standard deviation, showing the stability of coefficients to exclusion of each subject and the k-fold cross-validation coefficient standard deviation, showing stability of coefficients to excluding 10% of samples from the model in turn