Table 3.
Risk of gastric cardia and non-cardia adenocarcinoma in participants exposed to prediabetes or diabetes and in those exposed to prediabetes compared with normoglycaemic participants, expressed as hazard ratio (HR) and 95% confidence interval (CI)
| Exposure and outcome | Gastric adenocarcinoma | Crude modela | Multivariable modelb |
|---|---|---|---|
| Number | HR (95% CI) | HR (95% CI) | |
| Cardia adenocarcinoma | |||
| Normoglycaemic | 43 | Reference | Reference |
| Prediabetes or diabetes | 27 | 0.96 (0.59–1.56) | 0.94 (0.57–1.54) |
| Non-cardia adenocarcinoma | |||
| Normoglycaemic | 89 | Reference | Reference |
| Prediabetes or diabetes | 60 | 0.98 (0.70–1.36) | 0.97 (0.69–1.35) |
| Cardia adenocarcinoma | |||
| Normoglycaemic | 43 | Reference | Reference |
| Prediabetes | 25 | 1.28 (0.78–2.11) | 1.28 (0.78–2.12) |
| Non-cardia adenocarcinoma | |||
| Normoglycaemic | 92 | Reference | Reference |
| Prediabetes | 42 | 0.97 (0.67–1.40) | 0.97 (0.67–1.40) |
aAge was used as the time scale
bAdjusted for sex, calendar year, BMI, tobacco smoking status and education level at baseline; age was used as the time scale