Table 1.
Characteristic | Patients N (%) |
---|---|
Median age, years (range) | 50 (17–79) |
Sex | |
Male | 14 (56) |
Female | 11 (44) |
ECOG | |
0 | 11 (44) |
1 | 10 (40) |
2 | 4 (16) |
Histology | |
Paraganglionoma | 11 (44) |
Pheochromocytoma | 14 (56) |
Prior systemic therapy | |
Systemic adjuvant | 1 (4) |
Systemic advanced | 3 (12) |
None | 21 (84) |
Prior local therapy | |
Radiation only | 4 (16) |
Surgery only | 11 (44) |
Surgery and radiation | 5 (20) |
None | 5 (20) |
Stage | |
Metastatic | 23 (92) |
Locally advanced | 2 (2) |
Sites of metastases | |
Lymph nodes | 11 (44) |
Lung | 12 (48) |
Bone | 12 (48) |
Liver | 14 (56) |
Total baseline urinary metanephrines elevated | |
Yes | 15 (60) |
No | 6 (24) |
Missing | 4 (16) |
Reason for enrolment | |
Radiologic and/or biochemical PD | 20 (80) |
Symptomatic PD | 5 (20) |