Table 2.

Response to treatment (N = 25; 23 evaluable for response data)^a

Response
Best response
CR	0 (0)
PR	3 (13)
SD > 12 wks.	16 (70)
PD	4 (17)
Unknown	2
Disease control rate
(CR, PR, SD > 12 weeks)	19 (83%)
(95% CI)	(61–95%)
Overall response rate
(CR+PR)	3 (13%)
(95% CI)	(0.03–0.34)
PFS events
Progression	20 (80)
Death	1 (4)
Censored	4 (16)
(2 lost to follow-up 2 remain on study)
Median PFS, mths (95% CI)	13.4 (5.3–24.6)
Median time on treatment, mths (range)	12.4 (1.0–88.0)

^aSNP-10 did not have measureable disease at baseline but is included in the 23