Table 1.

Association between EMT markers and expression of S100 proteins in PDAC samples

		S100A2	S100A4	S100A6	S100A14	Vimentin	P-Cad	E-Cad	Slug	Twist	ZEB1	pSTAT3
S100A2	Pearson Correlation	1	0.246	.047	.121	−.001	0.173	0.170	0.030	0.057	0.301	−0.091
	Sig. (2-tailed)		0.181	0.801	0.517	0.994	0.351	0.362	0.872	0.760	0.100	0.627
	N	31	31	31	31	31	31	31	31	31	31	31
S100A4	Pearson Correlation	0.246	1	0.444*	−0.371*	0.042	0.074	−0.409*	0.207	0.310	0.428*	0.470**
	Sig. (2-tailed)	0.181		0.012	0.040	0.821	0.692	0.022	0.263	0.090	0.016	0.008
	N	31	31	31	31	31	31	31	31	31	31	31
S100A6	Pearson Correlation	0.047	0.444*	1	0.096	−0.007	−0.030	0.012	0.156	0.189	0.083	0.387*
	Sig. (2-tailed)	0.801	0.012		0.607	0.970	0.873	0.948	0.403	0.310	0.657	0.032
	N	31	31	31	31	31	31	31	31	31	31	31
S100A14	Pearson Correlation	0.121	−0.371*	0.096	1	−0.589***	0.338	0.828***	−0.088	−0.221	−0.264	−0.261
	Sig. (2-tailed)	0.517	0.040	0.607		0.000	0.063	0.000	0.636	0.232	0.152	0.155
	N	31	31	31	31	31	31	31	31	31	31	31
Vimentin	Pearson Correlation	−0.001	0.042	−0.007	−0.589***	1	−0.180	−0.422*	0.069	0.237	−0.035	0.283
	Sig. (2-tailed)	0.994	0.821	0.970	0.000		0.332	0.018	0.712	0.199	0.854	0.124
	N	31	31	31	31	31	31	31	31	31	31	31
P-Cad.	Pearson Correlation	0.173	0.074	−0.030	0.338	−0.180	1	0.426*	0.210	0.042	0.369*	−0.077
	Sig. (2-tailed)	0.351	0.692	0.873	0.063	0.332		0.017	0.257	0.823	0.041	0.680
	N	31	31	31	31	31	31	31	31	31	31	31
E-Cad.	Pearson Correlation	0.170	−0.409*	0.012	0.828***	−0.422*	0.426*	1	−0.203	−0.318	−0.176	−0.296
	Sig. (2-tailed)	0.362	0.022	0.948	0.000	0.018	0.017		0.273	0.081	0.345	0.106
	N	31	31	31	31	31	31	31	31	31	31	31
Slug	Pearson Correlation	0.030	0.207	0.156	−0.088	0.069	0.210	−0.203	1	0.233	0.310	0.056
	Sig. (2-tailed)	0.872	0.263	0.403	0.636	0.712	0.257	0.273		0.206	0.090	0.765
	N	31	31	31	31	31	31	31	31	31	31	31
Twist	Pearson Correlation	0.057	0.310	0.189	−0.221	0.237	0.042	−0.318	0.233	1	0.125	0.419*
	Sig. (2-tailed)	0.760	0.090	0.310	0.232	0.199	0.823	0.081	0.206		0.505	0.019
	N	31	31	31	31	31	31	31	31	31	31	31
ZEB1	Pearson Correlation	0.301	0.428*	0.083	−0.264	−0.035	0.369*	−0.176	0.310	0.125	1	0.122
	Sig. (2-tailed)	0.100	0.016	0.657	0.152	0.854	0.041	0.345	0.090	0.505		0.512
	N	31	31	31	31	31	31	31	31	31	31	31
p-STAT3	Pearson Correlation	−0.091	0.470**	0.387*	−0.261	0.283	−0.077	−0.296	0.056	0.419*	0.122	1
	Sig. (2-tailed)	0.627	0.008	0.032	0.155	0.124	0.680	0.106	0.765	0.019	0.512
	N	31	31	31	31	31	31	31	31	31	31	31

Asterisks indicate significant positive and negative correlations. *p < 0.05; **p < 0.01; ***p < 0.0001