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The QS system in P. aeruginosa. The scheme illustrates (in different colors) four main circuits of the QS system: AHL-dependent circuits, Las and Rhl, which are interconnected to the PQS circuit, and IQS. They can be triggered by certain stimuli, such as bacterial cell density or iron limitation, etc. Chemical structures are shown for four main QS signal molecules, 3-O-C12-HSL, C4-HSL, PQS, and IQS. Furthermore, the scheme shows QS-regulated products and cooperative behaviors.
