Table 2.
Differential abundance of AMPs among nonsmoking participants who were periodontally healthy and those with periodontal disease
| Peptide | Group | Fold change | p on log valuet test | p on log value ANCOVA (age-adjusted) |
|---|---|---|---|---|
| Ribonuclease 7 | nPnS/PnS | 19.3 | 0.001 | 0.001 |
| Protachykinin 1 | nPnS/PnS | 3.7 | 0.01 | 0.006 |
| β-Defensin128 | nPnS/PnS | 3.5 | 0.002 | 0.0005 |
| Lipocalin 1 | nPnS/PnS | 2.9 | 0.049 | 0.065 |
| BPIB3 | nPnS/PnS | 2.3 | 0.025 | 0.009 |
| Bone-marrow proteoglycan | nPnS/PnS | 2.1 | 0.015 | 0.02 |
| Neutrophil defensin 1 | nPnS/PnS | 0.3 | 0.034 | 0.048 |
| Cathelicidin | nPnS/PnS | 0.45 | 0.006 | 0.007 |
p values are based on Student’s t test and ANCOVA adjusted for age for independent samples on log10-transformed levels of AMPs. BPIB3, bactericidal permeability-increasing fold-containing family B member 3; nPnS, nonsmokers with no periodontal disease; PnS, nonsmokers with periodontal disease.