Table 3.

Differential abundance of AMPs in periodontally healthy smokers versus smokers with periodontal disease

Peptide	Group	Fold change	p value1	p value2
Adrenomedullin	PS/nPS	2.3	0.04	0.602
Eosinophil peroxidase	PS/nPS	2.2	0.025	0.153
Histone H2A type 2A	PS/nPS	2.6	0.028	0.183
Histone H2B type 2E	PS/nPS	2.2	0.046	0.310
Histone H2B type F-S	PS/nPS	2.0	0.042	0.245
Myeloperoxidase	PS/nPS	2.3	0.014	0.101
Neutrophil defensin 1	PS/nPS	2.3	0.021	0.082

p values are based on Student’st test and ANCOVA adjusted for age for independent samples on log₁₀-transformed levels of AMPs:

¹unadjusted

²adjusted for age. nPS, smokers with no periodontal disease; PS, smokers with periodontal disease.