Table 1.
HdE is not preferentially cytotoxic to murine bone marrow-derived neutrophils over a 16-h period
| Control | HdE, μg/mL |
Staurosporine 1 μM | Distilled H2O | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 100 |
500 |
1,000 |
|||||||||
| 4h | 16h | 4h | 16h | 4h | 16h | 4h | 16h | 4h | 16h | 4h | |
| % viable | 92±2 | 47±4 | 90±4 | 45±9 | 90±4 | 43±4 | 90±5 | 45±6 | 88±4 | 10±5 | nt |
| LDH (AU ×105) | 3.0±0.8 | nt | 3.4±0.9 | nt | 3.5±0.7 | nt | 2.7±0.7 | nt | nt | nt | 5.1±1.0 |
Data is mean ± SD, n = 4 mice for trypan blue % viability and n = 6 mice for lactate dehydrogenase (LDH); AU, arbitrary units; nt, not tested; h, hour; duplicate samples of neutrophils/mouse; HdE, Hymenolepis diminuta extract.