Fig. 1.

Hps3^coa mice have abnormal platelet δ granules with un­altered leukocyte granularity. a Platelet side-scatter. b Platelet counts. Platelet CD63 (c, e) and P-selectin (d, f) expression in Hps3^coa and control blood stimulated with 0.1 mg/mL (c, d) or 0.4 mg/mL (e, f) of PAR4AP. Plasma levels of serotonin (g) and CXCL4 (h) after stimulation with 0.4 mg/mL of PAR4AP. Neutrophil (i) and monocyte (j) counts. Neutrophil (k) and monocyte (l) side scatters. Data are represented as scatter dot plots of 4 mice per group. Lines show the median. *° p < 0.05 versus controls.