TABLE 1.

Clinical and demographic characteristics of MS patients and controls.

Characteristics	CTL (n = 24)	MS (n = 34)	p-value
Female, n (%)	15 (62.5)	22 (64.7)	>0.999
Age (years), mean (SD)	40.0 (11.2)	44.4 (10.8)	0.145
Age range	22–64	24–65
EDSS, median (IR)	n/a	1 (0, 3)
EDSS range	n/a	0–7
Disease duration, median (IR)	n/a	10 (6, 17)
Line of therapy, n (%)
No therapy		8 (23.5)
First line therapy	n/a	16 (47.1)
Second line therapy		10 (29.4)

First line therapy includes glatiramer acetate, interferons, and dimethyl fumarate. Second line therapy includes natalizumab, fingolimod. CTL, control group; EDSS, expanded disability status scale; MS, multiple sclerosis group; SD, standard deviation; IR, interquartile range; n/a, not applicable. Missing values [variable (n)]: EDSS (2); disease duration (2).