Table 3. The frequencies of haplotypes of ADAMTS7 gene in combined cohort.
Haplotypes | Case (freq%) | Control (freq%) | P valuea | OR (95% CI) |
ADAMTS7 (rs3825807, rs11634042, rs4380028, rs7173743) | ||||
A-C-C-T | 1093(42.8) | 974(38.4) | 1.00(reference) | |
A-C-T-C | 815(31.9) | 811(32.0) | 0.11 | 0.90(0.79-1.03) |
A-C-C-C | 176(6.9) | 188(7.4) | 0.11 | 0.82(0.66-1.03) |
G-T-T-C | 112(4.4) | 188(7.4) | 2.0×10-6 | 0.57(0.45-0.73) |
G-T-C-C | 99(3.9) | 147(5.8) | 3.6×10-4 | 0.50(0.38-0.66) |
Adjusted for age, gender, smoking, hypertension, diabetes mellitus and hyperlipidaemia.
All those frequency<0.05 will be ignored in analysis.
a False discovery rate-adjusted P value for multiple hypotheses testing using the Benjamini-Hochberg method.
P value under 0.05 was indicated in bold font.